Lecture 1. Genomes projects (06.03.2003 )

    Genomes projects
  1. H.influenzae – the first completely sequenced genome.
  2. The Human Genome Project. The history, organization and goals of the HGP
  3. The methodology for DNA sequencing. Automated DNA sequencing.
  4. Genome projects for model organisms.
  5. The S. cerevisiae genome project. The Mouse Genome projects .
  6. Genomics centers.
    Seminar’s discussions
  • Why are Genome Projects important?
  • Genetic and physical mapping of the human genome.
  • FISH and Sequence Tagged Site (STS) mapping.
  • Genome projects for E. coli, B. subtilis and A. fulgidus.
    Main reading
  1. Bioinformatics: Sequence and Genome Analysis / David W. Mount .- Cold Spring Harbor Laboratory Press , 2001. - Chapter 2. Collecting and Storing Sequences in the Laboratory.

Internet Resources

GenBank Entrez Genomes division
The Institute for Genome Research (TIGR) Microbial Database
Integrated Genomics Inc.
NHGRI List of Genetic and Genomic Resources
The Sanger Centre
Washington University-St.Louis
Microbial Genome Database
European Bioinformatics Institute
CAP3